The 10X Genomics Chromium Controller is a compact and user-friendly instrument designed for single-cell and spatial genomics library preparation. Renowned for its precise microfluidic technology, it enables efficient partitioning and barcoding of cells or nuclei, making it ideal for high-throughput sequencing workflows. Its small footprint fits well in any laboratory setting, supporting a broad range of advanced genomic applications. The controller's intuitive interface streamlines the workflow, facilitating rapid and reproducible sample processing. This instrument is essential for researchers aiming to advance their discoveries in transcriptomics, epigenomics, and spatial biology.