The Repligen KrosFlo KR2i Tangential Flow Filtration (TFF) System is a versatile and reliable instrument for biomolecule concentration and diafiltration. Designed for continuous operation, it offers precise control of fluid flow and pressure to optimize filtration efficiency. The system incorporates an integrated touchscreen interface for intuitive operation and real-time monitoring. It is ideal for research and pilot-scale bioprocessing applications, providing scalability and reproducibility. The KR2i combines peristaltic pumps with accessible valve control for flexible filtration protocols. Its modular design supports various filter cassettes and complements with dedicated scales for process measurement. Robust construction ensures long-term durability in demanding lab environments, making it a valuable tool for protein purification and cell harvest concentration processes.