The Caliper IVIS Spectrum is a highly versatile in vivo imaging system designed for bioluminescence, fluorescence, and X-ray imaging applications. It enables researchers to perform non-invasive monitoring of disease progression, gene expression, and molecular activities in live animals. The system offers advanced multispectral capabilities, optimizing detection sensitivity with precise spectral unmixing. Built for high throughput and reproducibility, it supports a wide range of preclinical research fields including oncology, immunology, infectious disease, and cardiovascular studies. The IVIS Spectrum provides high-resolution images with adjustable filters and cooling options to maintain sample viability. Its robust design ensures dependable operation in demanding research environments. Ideal for laboratories focusing on small animal imaging and longitudinal studies, it facilitates detailed temporal and spatial data acquisition.